CS Pro Digital SRL was established in 1997 by CME Media Enterprises BV, based in the Netherlands. Since its inception, the company has been managed by Cătălin Giosan. Initially, it was known as "Mediapro Mixed Enterprise SRL."

Over the years, CME Media Enterprises BV has undergone various changes in its shareholding structure. It was previously owned by Central European Media Enterprises NV in Curacao, which was wholly owned by Central European Media Enterprises Ltd, a closed limited liability company in Bermuda. This joint-stock company was listed on both the NASDAQ and Prague Stock Exchanges, with shares publicly traded.

In 2009, the media conglomerate Time Warner became the majority shareholder of CME, adding to its portfolio notable entities such as HBO, CNN, and Warner Bros. In 2016, it announced plans to be acquired by the American group AT&T in a deal valued at $85.4 billion. In 2019, Central European Media Enterprises signed a definitive agreement to sell to the investment fund PPF Group, controlled at the time by billionaire Petr Kellner, with the transaction valued at $2.1 billion.

Currently, CME Media Enterprises BV is 100% owned by TV Holdco BV, also based in the Netherlands, which in turn is wholly owned by PPF TMT Bidco 2 BV, established by PPF Group NV. PPF TMT Bidco 2 BV has several shareholders: Redimco SARL (0.535%), founded in Luxembourg by Czech businessman Ladislav Bartonicek; Flowervale SARL (0.535%), founded in Luxembourg by Belgian Jean Pascal Pierre A. Duvieusart; PPF Holdings BV (14.3%); and Renata Kellnerova (50.77%) from the Czech Republic. Renata is also the majority shareholder (60%) of PPF Holdings BV, alongside her four children—Petr, Anna, Lara, and Marie Isabella—who each hold 10% of the shares in PPF Holdings BV and 8.46% in PPF Group NV.